Liver Health Supplements: Are They Safe Or Unsafe?

Liver Health Supplements

Key highlights or summary

  • Supplements for liver health are substances that you eat or drink to supplement things like vitamins, minerals, enzymes, etc.
  • Some supplements are derived from natural sources like plants. They come in a variety of forms, including pills, tonics, and powders.
  • Many liver health supplements claim to detoxify and cleanse the liver. Some of these products treat liver problems, while others aggravate them.
  • According to some studies, herbal substances help the liver properly metabolize food, balance hormones, and eliminate waste.
  • The effectiveness of these herbal substances is debatable and not fully ascertained.
  • Though certain vitamins, herbal remedies, and other natural products can be beneficial in certain dosages, it is also possible that some of these supplements can be harmful to your liver.

Meet our expert

Meet our expert

Rate our article

We'd love to know!

  • 0
  • 0
  • 0
  • 1

How was the experience with article?

We'd love to know!

  1.  Navarro VJ, Khan I, Bjornsson E, Seeff LB, Serrano J, Hoofnagle JH. Liver Injury From Herbal and Dietary Supplements. J Hepatol. 2017 Jan;65(1). Available from: Aasldpubs
  2. Burnett AJ, Livingstone KM, Woods JL, McNaughton SA. Dietary Supplement Use among Australian Adults: Findings from the 2011-2012 National Nutrition and Physical Activity Survey. Nutrients. 2017 Nov;9(11). Available from: NIH
  3. Therapeutic Goods Administration (TGA). Medicines and TGA Classifications. Australian Government: Department of Health. Available from: TGA
  4. Autoimmune Hepatitis Associated With Turmeric Consumption, Lee, Brian S. MD1; Bhatia, Taruna MD2; Chaya, Charles T. MD2; Wen, Robert MD2; Taira, Mark T. MD3; Lim, Brian S. MD, MCR1,2, ACG Case Reports Journal: March 2020 - Volume 7 - Issue 3 - p e00320
  5. Abenavoli L, Izzo AA, Millić N, et al. Milk thistle (Silybum marianum): a concise overview of its chemistry, pharmacological and nutraceutical uses in liver diseases. Phytotherapy Research. 2018;32(11):2202-2213.
  6. Camini FC, Costa DC. Silymarin: not just another antioxidant. Journal of Basic and Clinical Physiology and Pharmacology. 2020;31(4): :/j/jbcpp.2020.31.issue-4/jbcpp-2019-0206/jbcpp-2019-0206.xml.
  7. Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial   
  8.  Yunes Panahi, Parisa Kianpour et al, Phytother Res. 2018 Jul;32(7):1382-1387. doi: 10.1002/ptr.6073. Epub 2018 Mar 9.
  9. Ladas EJ, et al. (2010). A randomized controlled, double-blind pilot study of milk thistle for the treatment of hepatotoxicity in childhood acute lymphoblastic leukemia (ALL). DOI:10.1002/cncr.24723
  10. Panahi Y, et al. (2018). Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial. DOI:10.1002/ptr.6073

Frequently asked questions

Get the information you need.

Supplements such as milk thistle, turmeric (curcumin), vitamin E, and omega-3 fatty acids are commonly used to support liver health.

Milk thistle contains silymarin, an antioxidant that may protect liver cells from toxins and support liver regeneration. Studies suggest it can improve liver function in certain liver diseases.

Turmeric's active compound, curcumin, has anti-inflammatory and antioxidant properties that may support liver health.

Vitamin E is an antioxidant that may help reduce inflammation and oxidative stress in the liver. Studies indicate it can be beneficial in managing non-alcoholic fatty liver disease.

Yes, liver supplements can have side effects and may interact with medications. For example, excessive intake of vitamin E can lead to toxicity. It's crucial to consult a healthcare provider before starting any supplement regimen.

Some supplements, like vitamin E, have shown potential benefits in managing non-alcoholic fatty liver disease. However, their use should be under medical supervision, as effectiveness varies among individuals.

N-Acetylcysteine (NAC) is a precursor to glutathione, a powerful antioxidant that helps protect liver cells from damage. It is sometimes used in clinical settings to treat acetaminophen overdose.

Dosages vary depending on the supplement and individual health conditions. For instance, vitamin E is often recommended at 800 IU daily for liver health, but it's essential to consult a healthcare provider for personalized advice.

Some herbal remedies, like milk thistle, can potentially support liver health. However, they should be used cautiously under medical supervision.

Omega-3 fatty acids have anti-inflammatory properties that may help reduce liver fat and inflammation, particularly in non-alcoholic fatty liver disease. Incorporating sources like flaxseeds, chia seeds, and walnuts into your diet can be beneficial.